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Title Methods in Molecular Biophysics
Author Nathan R. Zaccai
Publisher Cambridge University Press
Release Date 2017-05-18
Category Medical
Total Pages 702
ISBN 9781107056374
Language English, Spanish, and French
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Book Summary:

A comprehensive graduate textbook explaining key physical methods in biology, reflecting the very latest research in this fast-moving field.

Title Multiscale Methods in Molecular Biophysics
Author Cecilia Clementi
Publisher CRC Press
Release Date 2026-06-30
Category
Total Pages 320
ISBN 1482225700
Language English, Spanish, and French
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Book Summary:

Multiscale methods are ideally suited to simulate the processes at work in many biomolecular systems, which often span a large range of time and length scales. Multiscale Methods in Molecular Biophysicshighlights the advantages of these methods for integrating different levels of detail in a single simulation setting. It covers the practical methodology and successful applications in areas such as enzyme catalysis, protein folding, and ligand binding. The book is divided into three main sections: combination quantum and classical (atomistic) descriptions, approaches that combine atomistic and coarse-grained level of details, and multiscale methods where the resolution coupling is between global collective coordinates and local details.

Title Biophysical Labeling Methods in Molecular Biology
Author Gertz I. Likhtenshtein
Publisher Cambridge University Press
Release Date 1993-03-26
Category Medical
Total Pages 305
ISBN 9780521431323
Language English, Spanish, and French
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Book Summary:

This volume covers all aspects of this field: the theoretical bases, the experimental techniques, and it also shows how to interpret the resulting data.

Title Introduction to Experimental Biophysics
Author Jay Nadeau
Publisher CRC Press
Release Date 2011-09-21
Category Science
Total Pages 672
ISBN 9781439829530
Language English, Spanish, and French
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Book Summary:

Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often specific to particular subject areas; nonetheless, there are a few basic methods that provide a conceptual underpinning for broad application. Introduction to Experimental Biophysics is the ideal benchtop companion for physical scientists interested in getting their hands wet. Assuming familiarity with basic physics and the scientific method but no previous background in biology or chemistry, this book provides: A thorough description of modern experimental and analytical techniques used in biological and biophysical research Practical information and step-by-step guidance on instrumentation and experimental design Recipes for common solutions and media, lists of important reagents, and a glossary of biological terms used Developed for graduate students in biomedical engineering, physics, chemical engineering, chemistry, mathematics, and computer science, Introduction to Experimental Biophysics is an essential resource for scientists to overcoming conceptual and technical barriers to working in a biology wet lab.

Biophysics by Mark C. Leake

Title Biophysics
Author Mark C. Leake
Publisher CRC Press
Release Date 2016-09-15
Category Medical
Total Pages 390
ISBN 9781498702461
Language English, Spanish, and French
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Book Summary:

An Up-to-Date Toolbox for Probing Biology Biophysics: Tools and Techniques covers the experimental and theoretical tools and techniques of biophysics. It addresses the purpose, science, and application of all physical science instrumentation and analysis methods used in current research labs. The book first presents the historical background, concepts, and motivation for using a physical science toolbox to understand biology. It then familiarizes students from the physical sciences with essential biological knowledge. The text subsequently focuses on experimental biophysical techniques that primarily detect biological components or measure/control biological forces. The author describes the science and application of key tools used in imaging, detection, general quantitation, and biomolecular interaction studies, which span multiple length and time scales of biological processes both in the test tube and in the living organism. Moving on to theoretical biophysics tools, the book presents computational and analytical mathematical methods for tackling challenging biological questions. It concludes with a discussion of the future of this exciting field. Future innovators will need to be trained in multidisciplinary science to be successful in industry, academia, and government support agencies. Addressing this challenge, this textbook educates future leaders on the development and application of novel physical science approaches to solve complex problems linked to biological questions.

Title Methods in Modern Biophysics
Author Bengt Nölting
Publisher Springer Science & Business Media
Release Date 2013-03-09
Category Science
Total Pages 254
ISBN 9783662053676
Language English, Spanish, and French
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Book Summary:

Incorporating dramatic recent advances, "Methods in Modern Biophysics" presents a fresh and timely introduction to modern biophysical methods. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, and proteomics. Containing much information previously unavailable in tutorial form, "Methods in Modern Biophysics" employs worked examples and more than 260 illustrations to fully detail the techniques and their underlying mechanisms. The book was written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry, general biology and related fields.

Title Methods in Molecular Biophysics
Author Igor N. Serdyuk
Publisher Cambridge University Press
Release Date 2007-03-29
Category Science
Total Pages 1136
ISBN 052181524X
Language English, Spanish, and French
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Book Summary:

Our knowledge of biological macromolecules and their interactions is based on the application of physical methods, ranging from classical thermodynamics to recently developed techniques for the detection and manipulation of single molecules. These methods, which include mass spectrometry, hydrodynamics, microscopy, diffraction and crystallography, electron microscopy, molecular dynamics simulations, and nuclear magnetic resonance, are complementary; each has its specific advantages and limitations. Organised by method, this textbook provides descriptions and examples of applications for the key physical methods in modern biology. It is an invaluable resource for undergraduate and graduate students of molecular biophysics in science and medical schools, as well as research scientists looking for an introduction to techniques beyond their specialty. As appropriate for this interdisciplinary field, the book includes short asides to explain physics aspects to biologists and biology aspects to physicists.

Title Introduction to Biophysical Methods for Protein and Nucleic Acid Research
Author Jay A. Glasel
Publisher Academic Press
Release Date 1995-11-20
Category Science
Total Pages 510
ISBN 0080534988
Language English, Spanish, and French
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Book Summary:

The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment. Key Features * Modern Use of Mass Spectroscopy * NMR Spectroscopy * Molecular Modeling and Graphics * Macintosh and DOS/Windows 3.x disks

Title Molecular and Cellular Biophysics
Author Meyer B. Jackson
Publisher Cambridge University Press
Release Date 2006-01-12
Category Medical
Total Pages 512
ISBN 052162441X
Language English, Spanish, and French
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Book Summary:

Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Biophysics Of Dna by Alexander Vologodskii

Title Biophysics of DNA
Author Alexander Vologodskii
Publisher Cambridge University Press
Release Date 2015-03-12
Category Science
Total Pages 272
ISBN 9781107034938
Language English, Spanish, and French
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Book Summary:

Surveys the last sixty years of research in the rapidly advancing field of DNA biophysics, addressing key questions and facilitating further research.

Title Biophysical Methods in Cell Biology
Author Anonim
Publisher Academic Press
Release Date 2015-01-29
Category Science
Total Pages 568
ISBN 9780128013267
Language English, Spanish, and French
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Book Summary:

This new volume of Methods in Cell Biology looks at methods for analyzing of biophysical methods in cell biology. Chapters cover such topics as AFM, traction force microscopy, digital holographic microscopy, single molecule imaging, video force microscopy and 3D multicolor super-resolution screening Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

Title Structural Molecular Biology
Author David Davies
Publisher Springer Science & Business Media
Release Date 2013-03-09
Category Science
Total Pages 530
ISBN 9781468442205
Language English, Spanish, and French
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Book Summary:

Structural biology is undergoing a revolution in both the sophistication of new biophysical methods and the complexity of problems in biomolecular structure and organization opened up for study. These changes are directly attributable to major advances in computer technology, computational methods, development of high intensity synchrotron radiation sources, new magnetic resonance methods, laser optical techniques, etc. Structure-function problems previously considered intractable may now be solved. As this area of specialisation continues to expand, there is a need to review the various physical methods currently being used and developed in struc tural molecular biology. At the same time that individual techniques and their applications become more specialized, the need for effect ive communication between investigators gains in imperative. It is vital to forge links among sub-disciplines and to emphasise the complementary nature of results observed by different biophysical methods. This publication contains the review lectures given at a meeting on "Current Methods in Structural Molecular Biology" spon sored by NATO as an Advanced Study Institute and by FEBS ~s Advanced Course No. 78. The aim of the meeting was to bring together, in a teaching environment, students and specialists in diverse biophysical methodologies with the specific purpose of exploring, questioning and critically assessing the present and future state of biological structure research. The scientific content of the interdisciplinary Study Institute centred around three interrelated aspects; biophysical methods and instrumentation, their application to biological structure problems, and derivation of structural information and insights.

Title Statistical Methods in Molecular Biology
Author Heejung Bang
Publisher Humana Press
Release Date 2010-03-09
Category Science
Total Pages 636
ISBN 1607615789
Language English, Spanish, and French
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Book Summary:

This progressive book presents the basic principles of proper statistical analyses. It progresses to more advanced statistical methods in response to rapidly developing technologies and methodologies in the field of molecular biology.

Title Biophysics of Membrane Proteins
Author Vincent Postis
Publisher Humana
Release Date 2020-08-14
Category Science
Total Pages 337
ISBN 1071607235
Language English, Spanish, and French
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Book Summary:

This volume provides recent advances in the field of biophysics of membrane proteins. Chapters are divided into several parts: detailing biochemistry and functional analysis, experimental and theoretical structural determinations, membrane protein dynamics, and conformation studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Biophysics of Membrane Proteins: Methods and Protocols aims to provide comprehensive protocols with notes to help further the understanding of key membrane protein structure and function for students, academics, and industrial researchers.

Title Biophysical Techniques in Drug Discovery
Author Angeles Canales
Publisher Royal Society of Chemistry
Release Date 2017-11-14
Category Science
Total Pages 320
ISBN 9781788012867
Language English, Spanish, and French
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Book Summary:

Biophysical techniques are used in many key stages of the drug discovery process including in screening for new receptor ligands, in characterising drug mechanisms, and in validating data from biochemical and cellular assays. This book provides an overview of the biophysical methods applied in drug discovery today, including traditional techniques and newer developments. Perspectives from academia and industry across a spectrum of techniques are brought together in a single volume. Small and biotherapeutic approaches are covered and strengths and limitations of each technique are presented. Case studies illustrate the application of each technique in real applied examples. Finally, the book covers recent developments in areas such as electron microscopy with discussions of their possible impact on future drug discovery. This is a go-to volume for biophysicists, analytical chemists and medicinal chemists providing a broad overview of techniques of contemporary interest in drug discovery.

Title Methods in Modern Biophysics
Author Bengt Nölting
Publisher Springer Science & Business Media
Release Date 2009-10-05
Category Medical
Total Pages 273
ISBN 9783642030215
Language English, Spanish, and French
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Book Summary:

Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. It presents novel information, and is the first book to survey and explain the ten key biophysical methods.

Molecular Biophysics by M Volkenstein

Title Molecular Biophysics
Author M Volkenstein
Publisher Elsevier
Release Date 2012-12-02
Category Science
Total Pages 634
ISBN 9780323144186
Language English, Spanish, and French
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Book Summary:

Molecular Biophysics presents the fundamental principles of biophysics and their application to the study of the physical properties of biological macromolecules. The merger of biology and physics involves the development of sophisticated instrumentation and the molecular approach to the study of life phenomena. This book is composed of nine chapters and begins with an overview of the thermodynamical aspects and chemical foundations of biophysics. These topics are followed by the physical aspects of macromolecules, with a particular emphasis on the biological functions, conformation, and hydrophobic interactions of proteins. The subsequent chapter describes the structural and electro-optical properties of biopolymers based on X-ray, optical, and spectroscopic analysis. The discussion then shifts to enzymes, their chemical kinetics, catalytic potential, and conformational and cooperative properties. The remaining chapters explore the physical aspects of nucleic acids and the biosynthesis of proteins. This book will prove useful to molecular biophysicists, biologists, physicists, and researchers in the fields of life sciences.

Biophysical Techniques by Iain Campbell

Title Biophysical Techniques
Author Iain Campbell
Publisher Oxford University Press
Release Date 2012-02-16
Category Medical
Total Pages 353
ISBN 9780199642144
Language English, Spanish, and French
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Book Summary:

Biophysical Techniques explains in a readily-accessible way the basics of the various biophysical methods available so students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.

Theoretical Molecular Biophysics by Philipp O.J. Scherer

Title Theoretical Molecular Biophysics
Author Philipp O.J. Scherer
Publisher Springer
Release Date 2017-11-22
Category Science
Total Pages 513
ISBN 9783662556719
Language English, Spanish, and French
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Book Summary:

This book gives an introduction to molecular biophysics. It starts from material properties at equilibrium related to polymers, dielectrics and membranes. Electronic spectra are developed for the understanding of elementary dynamic processes in photosynthesis including proton transfer and dynamics of molecular motors. Since the molecular structures of functional groups of bio-systems were resolved, it has become feasible to develop a theory based on the quantum theory and statistical physics with emphasis on the specifics of the high complexity of bio-systems. This introduction to molecular aspects of the field focuses on solvable models. Elementary biological processes provide as special challenge the presence of partial disorder in the structure which does not destroy the basic reproducibility of the processes. Apparently the elementary molecular processes are organized in a way to optimize the efficiency. Learning from nature by means exploring the relation between structure and function may even help to build better artificial solar cells. The reader is exposed to basic concepts in modern biophysics, such as entropic forces, phase separation, potential of mean force, electron and proton transfer, heterogeneous reactions, coherent and incoherent energy transfer as well as molecular motors. Basic knowledge in classical and Quantum mechanics, electrostatics and statistical physics is desirable. Simplified models are presented which can be solved in limited cases analytically from the guiding lines to generate the basis for a fundamental understanding of the more complex biophysical systems. Chapters close with challenging problems whose solutions are provided at the end of the book to complete the pedagogical treatment in the book. To the second edition several new chapters were added. The medium polarization is treated self-consistently using basic elements of polaron theory and more advanced nonlinear Schrödinger equations to describe the dynamics of solvation. Ion transport through a membrane was extended by the discussion of cooperative effects. Intramolecular transitions are now discussed in the new edition in much more detail, including also radiationless transitions. Very recent developments in spectroscopy are included, especially two-dimensional and hole-burning spectroscopy. The discussion of charge transfer processes was extended by including recent results of hole transfer in DNA in connection with the super-exchange mechanism. The chapter on molecular motors was rewritten to include the most recent developments of new models. The book is a useful text for students and researchers wanting to go through the mathematical derivations in the theories presented. This book attracts a group of applied mathematically oriented students and scholars to the exciting field of molecular biophysics.

Title Wilson and Walker s Principles and Techniques of Biochemistry and Molecular Biology
Author Andreas Hofmann
Publisher Cambridge University Press
Release Date 2018-03-31
Category Medical
Total Pages 962
ISBN 9781107162273
Language English, Spanish, and French
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Book Summary:

A major update of a best-selling textbook that introduces students to the key experimental and analytical techniques underpinning life science research.