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Antibiotic Resistance by Institute of Medicine

Title Antibiotic Resistance
Author Institute of Medicine
Publisher National Academies Press
Release Date 2011-01-10
Category Medical
Total Pages 496
ISBN 9780309156110
Language English, Spanish, and French
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Book Summary:

Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Antibiotic Resistance by Kateryna Kon

Title Antibiotic Resistance
Author Kateryna Kon
Publisher Academic Press
Release Date 2016-06-14
Category Medical
Total Pages 436
ISBN 9780128036686
Language English, Spanish, and French
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Book Summary:

Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance. Discusses methods used to fight antibiotic-resistant infection based on a deep understanding of mechanisms involved in the development of the resistance Provides information on modern methods used to fight antibiotic resistance Covers a wide range of alternative methods to fight bacterial resistance, offering the most complete information available Discusses both newly emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments Offers the most up-to-date information in fighting antibiotic resistance Includes involvement of contributors all across the world, presenting questions of interest to readers of both developed and developing countries

Antibiotic Drug Resistance by José-Luis Capelo-Martínez

Title Antibiotic Drug Resistance
Author José-Luis Capelo-Martínez
Publisher John Wiley & Sons
Release Date 2019-09-24
Category Medical
Total Pages 720
ISBN 9781119282525
Language English, Spanish, and French
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Book Summary:

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

Antibiotic Resistance by Anthony R.M. Coates

Title Antibiotic Resistance
Author Anthony R.M. Coates
Publisher Springer Science & Business Media
Release Date 2012-10-23
Category Medical
Total Pages 192
ISBN 9783642289507
Language English, Spanish, and French
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Book Summary:

This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacteria. Ongoing resistance surveillance programs are also discussed, together with the perspective of a clinical microbiologist. The book then turns to specific themes such as the most serious area of resistance in pathogens, namely in Gram-negative organisms. The role of combinations of antibiotics in combating resistance emergence is discussed, particularly in the tuberculosis field, and then the importance of non-multiplying and persistent bacteria which are phenotypically resistant to antibiotics and prolong the duration of therapy of antibiotics which leads to poor compliance and resistance emergence. The role of anti-microbial compounds in textiles is covered, with its potential to exacerbate the spread of resistance. Then, efflux pumps are discussed. The final chapter describes the compounds which are in late stage clinical development, illustrating the paucity of the antibiotic pipeline, especially for Gram-negative bacteria.

Title Mechanisms of antibiotic resistance
Author Jun Lin
Publisher Frontiers Media SA
Release Date 2015-06-01
Category
Total Pages 86
ISBN 9782889195268
Language English, Spanish, and French
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Book Summary:

Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Title Bacterial Resistance to Antimicrobials Second Edition
Author Richard G. Wax
Publisher CRC Press
Release Date 2007-12-05
Category Science
Total Pages 448
ISBN 1420008757
Language English, Spanish, and French
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Book Summary:

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Understanding mechanisms of resistance is crucial to the future of antimicrobial therapy. Extensively revised, with contributions from international leaders in their fields, Bacterial Resistance to Antimicrobials, Second Edition blends scientific and practical approaches to the social, economic, and medical issues related to this growing problem. The book begins with a history of antimicrobial agents and bacterial resistance, and outlines the forces that contributed to the abuse of antibiotics and precipitated the current crisis. It goes on to describe what is known about the ecology of antibiotic resistant bacteria and reveals the inadequacies in our understanding. Emphasizing public health aspects, the editors stress that significant progress will be made only by addressing the problem only as a public, worldwide, problem. Chapters on resistance mechanisms describe the latest findings on what makes different groups of bacteria susceptible or resistant to antibiotics. They reveal the staggering diversity of bacteria and the need for a foundational understanding that will stimulate development of antibiotics capable of avoiding resistance mechanisms. Examining the success and limitations of complementary approaches, such as combining ß-lactam antibiotics with ß-lactamase inhibitors, the book brings together information on resistance mechanisms in different groups of bacteria to help future efforts to more effectively develop and deploy antimicrobial therapies.

Title Antibiotics and Antibiotic Resistance
Author Ola Sköld
Publisher John Wiley & Sons
Release Date 2011-10-07
Category Medical
Total Pages 224
ISBN 9781118075586
Language English, Spanish, and French
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Book Summary:

This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about antibiotics will help future scientists recognize the problem antibiotics resistance poses for medicinal and drug-related fields, and perhaps trigger more research and discoveries to fight antibiotic resistant strains. Current overviews of the topic are included, along with specific discussions on the individual mechanisms (betalactams, glycopeptides, aminoglycosides, etc) used in various antibacterial agents and explanations of how resistances to those develop. Methods for counteracting resistance development in bacteria are discussed as well.

Antibiotic Resistant Bacteria by Patrick Guilfoile

Title Antibiotic Resistant Bacteria
Author Patrick Guilfoile
Publisher Infobase Publishing
Release Date 2007
Category Medical
Total Pages 128
ISBN 9781438101323
Language English, Spanish, and French
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Book Summary:

This continuing series explores different diseases to show the science behind how disease-causing organisms affect the body. Microorganisms have plagued humans since the beginning of time, causing debilitating diseases and even death. But how, exactly, do these microorganisms infect and cause disease? The books in this series examine various microbiological scourges that have affected humans as well as the steps that have been taken to identify, isolate, prevent, and eradicate them. Each title will outline the history and treatments of the diseases, highlighting how improvements in prevention and treatment techniques have affected the disease's impact on the world population.

Title Antibiotic Resistance in Aquatic Systems
Author Satoru Suzuki
Publisher Frontiers Media SA
Release Date 2017-04-10
Category
Total Pages 86
ISBN 9782889451319
Language English, Spanish, and French
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Book Summary:

Rivers, lakes and the ocean receive antibiotic resistance genes from human environments. The aquatic environments are a huge reservoir and exchange stage of antibiotic resistance genes.

Antibiotic Resistance by S. H. Gillespie

Title Antibiotic Resistance
Author S. H. Gillespie
Publisher Springer Science & Business Media
Release Date 2001
Category Medical
Total Pages 287
ISBN 9781592590773
Language English, Spanish, and French
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Book Summary:

At a time of rising concern about drug resistance and falling output of new antibacterial compounds, antibiotic research has once again returned to the forefront of medical science. In Antibiotic Resistance: Methods and Protocols, Stephen Gillespie and a panel of leading clinical and diagnostic microbiologists describe a series of detailed molecular and physical methods designed to study the growing problem of antibiotic resistance, as well as facilitate new antibiotic research programs for its effective redress. The techniques range widely from those that provide rapid diagnosis via DNA amplification and phage display, to those for plotting the transmission of resistant organisms and investigating their epidemiology. The methods are readily adaptable to a wide range of resistant bacterial organisms. In order to ensure successful results, each method is described in minute detail and includes tips on avoiding pitfalls. Practical and wide-ranging, Antibiotic Resistance: Methods and Protocols provides a collection of indispensable techniques not only for illuminating the basic biology of antimicrobial resistance, but also for developing and implementing new diagnostic and epidemiological tools.

Antibiotic Resistance Protocols by Stephen H. Gillespie

Title Antibiotic Resistance Protocols
Author Stephen H. Gillespie
Publisher Humana PressInc
Release Date 2010-04-16
Category Medical
Total Pages 236
ISBN STANFORD:36105211741231
Language English, Spanish, and French
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Book Summary:

In order to reflect developments in the field of antibiotic resistance this book begins with chapters on epidemiology and population genetics before continuing with sections covering genomics and gene expressions, fitness mutation and physiology and the detection of resistance.

Title Bacterial Resistance to Antibiotics
Author Boyan B. Bonev
Publisher John Wiley & Sons
Release Date 2019-06-10
Category Science
Total Pages 288
ISBN 9781119940777
Language English, Spanish, and French
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Book Summary:

AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.

Title Antibiotics and Antibiotic Resistance in the Environment
Author Carlos F. Amabile-Cuevas
Publisher CRC Press
Release Date 2015-12-30
Category Medical
Total Pages 136
ISBN 9781315679419
Language English, Spanish, and French
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Book Summary:

The presence of antibiotics, antibiotic resistance genes, and antibiotic resistant bacteria in the environment (i.e., outside of clinical settings, such as antibiotic-treated patients or antibiotic-impregnated locations, such as hospitals) is a cause of growing worldwide concern, as it reveals the extensive impact of antibiotic abuse and other huma

Title Antibiotics and Antimicrobial Resistance Genes in the Environment
Author Muhammad Zaffar Hashmi
Publisher Elsevier
Release Date 2019-11-22
Category Science
Total Pages 432
ISBN 9780128188835
Language English, Spanish, and French
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Book Summary:

Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches. Summarizes and updates information on antibiotics and AMR/ARGs production and its fate and transport in the environment Includes phytoremediation and bioremediation technologies for environmental management Provides analysis of risk assessment of antibiotic resistance genes to help understand the environmental and socioeconomic impacts of antibiotics and AMR/ARGs

Antibiotic Resistance by H. g. Brack

Title Antibiotic Resistance
Author H. g. Brack
Publisher Createspace Independent Publishing Platform
Release Date 2016-05-05
Category
Total Pages 230
ISBN 1533029997
Language English, Spanish, and French
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Book Summary:

Volume 4 of the Phenomenology of Biocatastrophe publication series provides timely commentary and updates on the emergence and growth of antibiotic resistant and viral infections, as well as on other important widespread threats to human health such as the Zika outbreak, Legionnaire's disease, norovirus infections, and the rapid increase in Lyme disease. There is a broad spectrum of antibiotic resistant microbes (ARMs) now impacting a wide variety of bacteria, fungi, pathogens, and other microbial communities. The venues for their identification are the same hospitals, clinics, and research laboratories that lead to the pioneering adaptation of antimicrobial organisms to fight infectious diseases in developed and developing nations. In the United States, the CDC (Center for Disease Control) is the most important source of information on acquired bacterial resistance in human health, including its proliferation in the general community. The CDC publication, "Antibiotic Resistance: Threats in the United States, 2013" is reprinted in its entirety in Appendix 1 of this text.

Title Antimicrobial Resistance in Bacteria of Animal Origin
Author Frank M. Aarestrup
Publisher Amer Society for Microbiology
Release Date 2006-01
Category Medical
Total Pages 442
ISBN 1555813062
Language English, Spanish, and French
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Book Summary:

Antimicrobial Resistance in Bacteria of Animal Origin comprehensively examines the current research on antimicrobial resistance in the main veterinary and zoonotic pathogens, including resistance to disinfectants and metals used in agriculture.

Antibiotic Resistance by Karl S. Drlica

Title Antibiotic Resistance
Author Karl S. Drlica
Publisher FT Press
Release Date 2010-11-24
Category Medical
Total Pages 288
ISBN 0132117320
Language English, Spanish, and French
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Book Summary:

Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.

Antibiotic Resistance by U.S. Food and Drug Administration

Title Antibiotic Resistance
Author U.S. Food and Drug Administration
Publisher GPO FCIC
Release Date 2009
Category
Total Pages 86
ISBN 1612210333
Language English, Spanish, and French
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Book Summary:

Antibiotic drugs can save lives. But the more often you use an antibiotic, the more likely it is that germs will become drug resistant. Learn what you can do to minimize this problem.

Title Antimicrobial Resistance in Agriculture
Author Indranil Samanta
Publisher Academic Press
Release Date 2019-09-25
Category Medical
Total Pages 392
ISBN 9780128165232
Language English, Spanish, and French
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Book Summary:

Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans. Explores all the genera of livestock and fish originated pathogenic bacteria associated with antimicrobial resistance Presents cutting-edge research on epigenetics, nanotechnology and intervention technologies Discusses transmission dynamics of resistance gene pools from different reservoirs, including food animals, poultry, fishes and the environment

Title Antimicrobial Resistance and Food Safety
Author Chin-Yi Chen
Publisher Elsevier
Release Date 2015-04-15
Category Technology & Engineering
Total Pages 452
ISBN 9780128013373
Language English, Spanish, and French
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Book Summary:

Antimicrobial Resistance and Food Safety: Methods and Techniques introduces antimicrobial resistant food-borne pathogens, their surveillance and epidemiology, emerging resistance and resistant pathogens. This analysis is followed by a systematic presentation of currently applied methodology and technology, including advanced technologies for detection, intervention, and information technologies. This reference can be used as a practical guide for scientists, food engineers, and regulatory personnel as well as students in food safety, food microbiology, or food science. Includes analysis of all major pathogens of concern Provides many case studies and examples of fundamental research findings Presents recent advances in methodologies and analytical software Demonstrates risk assessment using information technologies in foodborne pathogens